Comprehensive Alcohol Research Centers (P60 Clinical trial Optional) | RFA AA 22 002

Opportunity Information: Apply for RFA AA 22 002

The Comprehensive Alcohol Research Centers (P60 Clinical Trial Optional) funding opportunity (RFA-AA-22-002) is a National Institutes of Health (NIH) grant that supports the creation or continuation of large, coordinated research centers focused on alcohol-related science. Using the NIH P60 Comprehensive Research Center mechanism, the program is designed to fund an integrated, long-term research effort that brings together multiple investigators and disciplines under a single, clearly defined major research theme. The intent is not to fund isolated projects, but to build a cohesive center program that can sustain a broad-based portfolio of studies and shared research-support activities that strengthen and accelerate progress in alcohol research. Clinical trials are optional under this announcement, meaning applicants may propose clinical trial work if it fits the center theme and goals, but clinical trials are not required.

The opportunity falls under the Health funding activity category and is associated with CFDA number 93.273. As a discretionary grant program administered by NIH, it supports comprehensive, multidisciplinary approaches that typically require coordination across different scientific areas (for example, basic biomedical science, clinical research, behavioral science, population health, and translational work). A core expectation of a P60 center is that the whole is greater than the sum of its parts: the center structure should create synergy, shared resources, and strategic alignment among investigators to advance a central alcohol-related research agenda over time.

Eligibility is broad across government, academic, nonprofit, and industry applicants. Eligible applicants include state, county, city or township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities/Indian housing authorities; and Native American tribal organizations that are not federally recognized tribal governments. The announcement also permits nonprofits with and without 501(c)(3) status (when not institutions of higher education), for-profit organizations (other than small businesses), and small businesses. In addition, NIH explicitly highlights other eligible applicant types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs). Faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions are also included among eligible applicants, reflecting an interest in expanding participation across institution types and communities.

At the same time, there are important restrictions related to non-U.S. entities and activities. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply as the applicant organization, and non-domestic components of U.S. organizations are not eligible to apply. However, foreign components are allowed as defined by the NIH Grants Policy Statement, which means a U.S.-based applicant may include certain types of foreign involvement when justified scientifically and structured in accordance with NIH policy (for example, specific collaborations or elements of the research that require access to unique populations or resources), even though the primary applicant institution must be domestic.

Key administrative details include an original closing date of November 15, 2022, and an award ceiling listed at $1,250,000. The funding opportunity was created on April 14, 2022. The listing does not specify an expected number of awards in the provided source text, but the ceiling indicates the maximum award level anticipated per award under this announcement. Overall, this FOA is geared toward institutions capable of running a multi-investigator center-level program in alcohol research, with a strong emphasis on integration, shared infrastructure and support activities, and sustained progress around a unifying scientific theme.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Comprehensive Alcohol Research Centers (P60 Clinical trial Optional)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273.
• This funding opportunity was created on 2022-04-14.
• Applicants must submit their applications by 2022-11-15. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $1,250,000.00 in funding.
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for RFA AA 22 002

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