Opportunity Information: Apply for HT9425 23 LRP IPA

The Lupus Research Impact Award (Funding Opportunity Number: HT9425 23 LRP IPA) is a Department of Defense research funding opportunity administered through the U.S. Army Medical Research Acquisition Activity (USAMRAA). It is designed to support high-impact lupus research across a broad range of scientific and clinical topics, with an emphasis on projects that could meaningfully advance the field if successful. The program is positioned to fund work that addresses important lupus-related problems, whether those problems are rooted in basic disease mechanisms, translational research, clinical investigation, or other research and development efforts that could influence how lupus is understood, diagnosed, or managed.

A central expectation of this award is that applicants propose a clearly defined, testable hypothesis backed by a strong scientific rationale. That rationale should be established through careful reasoning and a critical analysis of existing evidence, such as a thorough review of the scientific literature and logical inferential argumentation. In practical terms, the opportunity is looking for proposals that are not just interesting or exploratory, but structured around a solid justification for why the idea should work and why it matters to lupus. The focus on “impact” signals that reviewers will likely prioritize projects that could shift current thinking, solve a recognized bottleneck, or open a realistic path toward improved outcomes for people with lupus.

The funding mechanism allows for either grants or cooperative agreements, indicating that awards may range from traditional investigator-led projects to projects that involve more substantial involvement or coordination with the funding agency, depending on the specific award structure used. The activity category is Science and Technology and other Research and Development (CFDA: 12.420). Eligibility is broadly open, described as unrestricted, meaning that any entity type may apply as long as it meets any additional eligibility conditions stated in the full announcement.

The opportunity was created on April 17, 2023, with an original application closing date of August 10, 2023. The announcement anticipated making about five awards. The listed award ceiling is shown as 0, which typically signals that the maximum funding amount is not specified in the summary record and would need to be confirmed in the full funding announcement or related program documents.

  • The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "Lupus Research Impact Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
  • This funding opportunity was created on Apr 17, 2023.
  • Applicants must submit their applications by Aug 10, 2023. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 5 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Frequently Asked Questions (FAQs) - Lupus Research Impact Award (HT9425 23 LRP IPA)

What is the Lupus Research Impact Award?

The Lupus Research Impact Award is a Department of Defense (DoD) research funding opportunity intended to support high-impact lupus research across a wide range of scientific and clinical topics, with a focus on projects that could meaningfully advance the field if successful.

What is the Funding Opportunity Number (FON) for this program?

The Funding Opportunity Number is HT9425 23 LRP IPA.

Which government organization is offering and administering this opportunity?

This is a Department of Defense funding opportunity administered through the U.S. Army Medical Research Acquisition Activity (USAMRAA).

What types of lupus research topics are supported?

The program is designed to support a broad range of lupus-related research and development topics, including basic disease mechanisms, translational research, and clinical investigation, as well as other efforts that could influence how lupus is understood, diagnosed, or managed.

What does "impact" mean in the context of this award?

The emphasis on impact indicates that the opportunity is looking for projects with the potential to significantly advance lupus research if successful. This may include work that shifts current thinking, solves a recognized bottleneck, or creates a realistic path toward improved outcomes for people with lupus.

Is exploratory research a good fit for this funding opportunity?

Based on the description, the opportunity prioritizes proposals that are not just interesting or exploratory, but are structured around a clearly justified, testable idea with a strong rationale for why the approach should work and why it matters to lupus.

Is a hypothesis required in the application?

Yes. A central expectation is that applicants propose a clearly defined, testable hypothesis.

What level of justification is expected for the hypothesis and research approach?

The opportunity expects a strong scientific rationale supported by careful reasoning and a critical analysis of existing evidence. Examples of the types of support mentioned include a thorough review of the scientific literature and logical inferential argumentation.

What funding mechanisms may be used for awards under this opportunity?

The funding mechanism allows for either grants or cooperative agreements. This suggests awards may range from traditional investigator-led projects to projects that involve more substantial involvement or coordination with the funding agency, depending on the award structure used.

What is the activity category and CFDA listing for this opportunity?

The activity category is Science and Technology and other Research and Development, and the CFDA listing is 12.420.

Who is eligible to apply?

Eligibility is described as unrestricted, meaning any entity type may apply, as long as it meets any additional eligibility conditions that may be stated in the full announcement.

Are there additional eligibility conditions beyond "unrestricted"?

The summary indicates eligibility is unrestricted, but also notes applicants must meet any additional eligibility conditions stated in the full announcement.

When was this funding opportunity created?

The opportunity was created on April 17, 2023.

What was the original application closing date?

The original application closing date was August 10, 2023.

How many awards were anticipated?

The announcement anticipated making about five awards.

What is the maximum award amount (award ceiling) for this opportunity?

The listed award ceiling is shown as 0 in the summary record. This typically means the maximum funding amount is not specified in the summary and would need to be confirmed in the full funding announcement or related program documents.

Does the summary record provide the full funding details?

No. The summary notes that some key details (such as the practical maximum funding amount, given the ceiling appears as 0) would need to be confirmed in the full funding announcement or related program documents.

What kinds of outcomes is the program ultimately trying to influence?

Based on the description, the program supports work that could influence how lupus is understood, diagnosed, or managed, with an emphasis on research that could make a meaningful difference in the field if successful.

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DOD Peer Reviewed Orthopaedic, Applied Research Award Apply for HT9425 23 PRORP ARA

Funding Number: HT9425 23 PRORP ARA
Agency: Department of Defense, Dept. of the Army -- USAMRAA
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Determining drivers of floodplain forest regeneration success and failure on the Upper Mississippi River in Minnesota and Wisconsin Apply for W81EWF 23 SOI 0010

Funding Number: W81EWF 23 SOI 0010
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Category: Science and Technology and other Research and Development
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DOD Peer Reviewed Orthopaedic, Clinical Trial Award Apply for HT9425 23 PRORP CTA

Funding Number: HT9425 23 PRORP CTA
Agency: Department of Defense, Dept. of the Army -- USAMRAA
Category: Science and Technology and other Research and Development
Funding Amount: Case Dependent
DOD Peer Reviewed Orthopaedic, Clinical Translational Research Award Apply for HT9425 23 PRORP CTRA

Funding Number: HT9425 23 PRORP CTRA
Agency: Department of Defense, Dept. of the Army -- USAMRAA
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Funding Amount: Case Dependent
CULTURAL RESOURCES PROGRAM SUPPORT FORT A. P. HILL, VA Apply for W9126G 23 2 SOI 2302

Funding Number: W9126G 23 2 SOI 2302
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DOD, Rare Cancers, Concept Award Apply for HT9425 23 RCRP CA

Funding Number: HT9425 23 RCRP CA
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Funding Number: HT9425 23 RCRP IDA
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