Opportunity Information: Apply for W81XWH 20 LRP TVA
The Department of Defense Lupus Research Program (LRP) Transformative Vision Award (TVA) is a competitive research funding opportunity designed to support bold, high-risk, high-reward projects that could rapidly and dramatically improve the day-to-day quality of life for people living with lupus. The central expectation is that applicants propose an "extraordinary vision" for change and back it up with a clear, feasible plan to test that vision through translation-focused research, meaning the work should be positioned to produce near-term, real-world benefits rather than only longer-horizon basic science insights. Projects can focus on lupus patients of any age and may address a wide range of quality-of-life challenges, explicitly including issues affecting groups that carry disproportionate health burdens.
A key feature of this award is its strong emphasis on impact. Applications are expected to state plainly what will change for lupus patients if the project succeeds, why that change matters, and how quickly those benefits could be realized. The program is looking for research that goes beyond incremental progress and instead has the potential to shift clinical practice, care delivery, symptom control, functional status, or other patient-centered outcomes in a meaningful way. The proposal should make the case that the study is significant, that the magnitude of the potential benefit is substantial, and that the approach is plausible enough to justify the program's willingness to fund higher-risk ideas.
From a scientific and technical standpoint, the research strategy must show deep understanding of lupus and present a well-reasoned rationale supported by preliminary data, which are required. The experimental approach can be novel, but it still needs to be grounded in strong logic, existing evidence, and a clear methodology. Importantly, animal research is not permitted under this announcement, so the work must be structured around human subjects research, human-based methods, and/or clinical studies. Clinical trials are explicitly allowed, which signals that the program is open to intervention testing when justified and responsibly designed.
The award also evaluates whether the research team is appropriately qualified to carry out the proposed work. Reviewers will look for a team whose expertise matches the project needs, including the clinical, translational, methodological, and operational capabilities required to deliver results on a near-term timeline. The program includes a Partnering Principal Investigator option, allowing collaborative leadership across institutions or disciplines. One Initiating PI leads the administrative submission and coordination, and up to two additional Partnering PIs may be named. If funded, each PI receives an individual award under the recipient organization, reflecting the expectation that each PI plays a meaningful role in developing and executing the project.
Applicants must align their project with the FY20 LRP Focus Area for the Transformative Vision Award, making topic fit a hard requirement rather than a preference. In addition, the work must be relevant to active duty Service members, Veterans, military beneficiaries, and/or the broader American public, which is a standard DoD requirement and should be addressed directly in the application narrative rather than assumed.
Funding is provided through assistance agreements, which can be either a grant or a cooperative agreement depending on how much involvement the DoD anticipates during the project. If the agency expects no substantial involvement, it will typically issue a grant; if it expects substantial involvement (such as collaboration, participation, or intervention in the research), it will use a cooperative agreement and spell out that involvement in the award terms. For FY20, the maximum total cost for the full period of performance is capped at $2,500,000 per award, and budgets must be well-justified and consistent with the program announcement's limits and restrictions.
In terms of scale and competitiveness, the program expected to allocate about $2.5 million total and anticipated funding roughly one to two awards, making selection highly competitive and strongly driven by scientific merit, programmatic fit, and the credibility of the near-term quality-of-life impact. The opportunity (W81XWH-20-LRP-TVA) was posted by the Department of Defense, U.S. Army Medical Research Acquisition Activity (USAMRAA), with an original application closing date of September 23, 2020, and anticipated awards made no later than September 30, 2021. Funding was expected to come from FY20 funds, with availability for use limited by fiscal rules, and those funds projected to expire for use on September 30, 2026. Eligibility is broadly described as unrestricted (open to many organization types), subject to any specific clarifications in the full announcement.Apply for W81XWH 20 LRP TVA
- The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Lupus, Transformative Vision Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
- This funding opportunity was created on May 29, 2020.
- Applicants must submit their applications by Sep 23, 2020. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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| DoD Lupus, Idea Award Apply for W81XWH 20 LRP IA Funding Number: W81XWH 20 LRP IA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Species Mgt Natural Resources Spt Edwards AFB, CA Apply for W9126G 20 2 SOI 4172 Funding Number: W9126G 20 2 SOI 4172 Agency: Department of Defense, Fort Worth District Category: Science and Technology and other Research and Development Funding Amount: $584,427 |
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| Cooperative Ecosystem Studies Unit, Colorado Plateau CESU Apply for G20AS00050 Funding Number: G20AS00050 Agency: Department of the Interior, U. S. Geological Survey Category: Science and Technology and other Research and Development Funding Amount: $1,000,000 |
| NASA Innovative Advanced Concepts (NIAC) Phase I Apply for 80HQTR20NOA01 21NIAC A1 Funding Number: 80HQTR20NOA01 21NIAC A1 Agency: National Aeronautics and Space Administration Category: Science and Technology and other Research and Development Funding Amount: $125,000 |
| DoD Kidney Cancer, Clinical Consortium – Clinical Trial Site Award Apply for W81XWH 20 KCRP CTSA Funding Number: W81XWH 20 KCRP CTSA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Kidney Cancer, Postdoctoral and Clinical Fellowship Award Apply for W81XWH 20 KCRP PCFA Funding Number: W81XWH 20 KCRP PCFA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Kidney Cancer, Idea Development Award Apply for W81XWH 20 KCRP IDA Funding Number: W81XWH 20 KCRP IDA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Environmental DNA Sampling in the Lower Roanoke River Apply for W81EWF 20 SOI 0023 Funding Number: W81EWF 20 SOI 0023 Agency: Department of Defense, Dept. of the Army -- Corps of Engineers Category: Science and Technology and other Research and Development Funding Amount: $40,000 |
| Best Practices in Exporting Expertise Latin America and sub-Saharan Africa Apply for SFOP0007039 Funding Number: SFOP0007039 Agency: Department of State, Bureau of Global Public Affairs Category: Science and Technology and other Research and Development Funding Amount: $1,000,000 |
| Understanding thermal mixing, water quality improvements, and algae dynamics with the pulsing of releases from Jordan Reservoir Apply for W81EWF 20 SOI 0026 Funding Number: W81EWF 20 SOI 0026 Agency: Department of Defense, Dept. of the Army -- Corps of Engineers Category: Science and Technology and other Research and Development Funding Amount: $25,000 |
| Update the Standard Assessment Methodology (SAM) Model Apply for W81EWF 20 SOI 0027 Funding Number: W81EWF 20 SOI 0027 Agency: Department of Defense, Dept. of the Army -- Corps of Engineers Category: Science and Technology and other Research and Development Funding Amount: $110,000 |
| Investigating Uncertainty Associated with the Great Lakes Water Balance Apply for W81EWF 20 SOI 0028 Funding Number: W81EWF 20 SOI 0028 Agency: Department of Defense, Dept. of the Army -- Corps of Engineers Category: Science and Technology and other Research and Development Funding Amount: $85,000 |
| Studies on Nutrient & Algae/Cyanobacteria Removal in Backwater Areas of the Mississippi River Apply for W81EWF 20 SOI 0030 Funding Number: W81EWF 20 SOI 0030 Agency: Department of Defense, Dept. of the Army -- Corps of Engineers Category: Science and Technology and other Research and Development Funding Amount: $40,000 |
| Development and Validation of Reservoir and Riverine Water Quality Models Apply for W81EWF 20 SOI 0033 Funding Number: W81EWF 20 SOI 0033 Agency: Department of Defense, Dept. of the Army -- Corps of Engineers Category: Science and Technology and other Research and Development Funding Amount: $350,000 |
| Wetland accretion and vegetation growth model integration and application to coastal wetland management Apply for W81EWF 20 SOI 0032 Funding Number: W81EWF 20 SOI 0032 Agency: Department of Defense, Dept. of the Army -- Corps of Engineers Category: Science and Technology and other Research and Development Funding Amount: $15,000 |
| Mapping Russian Disinformation and Propaganda in sub-Saharan Africa Apply for SFOP0007033 Funding Number: SFOP0007033 Agency: Department of State, Bureau of Global Public Affairs Category: Science and Technology and other Research and Development Funding Amount: $600,000 |
| Comparison of Fish Assemblages of the Crutcho Creek Drainage Basin, Oklahoma (Tinker Air Force Base) Apply for W81EWF 20 SOI 0034 Funding Number: W81EWF 20 SOI 0034 Agency: Department of Defense, CEERD-CERL Category: Science and Technology and other Research and Development Funding Amount: $55,000 |
| Technical Assistance with Vegetation Data to Assess Treatment Success of Sagebrush Restoration Efforts at Great Basin National Park Apply for P20AS00083 Funding Number: P20AS00083 Agency: Department of the Interior, National Park Service Category: Science and Technology and other Research and Development Funding Amount: $54,000 |
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